黄嘌呤检测试剂盒 Xanthine Assay Kit

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市场价（人民币）

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MXA4685

黄嘌呤检测试剂盒 Xanthine Assay Kit

100 tests

1280.00

In stock

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产品概述
Description Xanthine is a purine base that can be found in most animal tissues and fluids. It is a product in the purine degradation pathway, produced by guanine deaminase from guanine, and by xanthine oxidoreductase from hypoxanthine. Xanthine is degraded to uric acid by xanthine oxidase. Clinically, xanthine and its derivatives act on sleep-inducing adenosine receptors as antagonists. Simple, direct and high-throughput assays for measuring xanthine find wide applications in research and drug discovery. MesGen Biotechnology xanthine assay kit uses a single Working Reagent that combines the xanthine oxidase reaction and color reaction in one step. The change in color intensity of the reaction product at 570 nm or fluorescence intensity at lex/em = 530/585 nm is directly proportional to xanthine concentration in the sample. Application Direct Assays: xanthine concentration in cell lysate, serum, and other biological samples. Drug Discovery/Pharmacology: effects of drugs on xanthine (purine) metabolism. Key features Sensitive and accurate. Use as little as 10 μL samples. Linear detection range in 96-well plate for 10-15 minute incubation: 2 μM to 1 mM xanthine for colorimetric assays and 0.5 to 200 μM for fluorimetric assays. Simple and convenient. The procedure involves addition of a single working reagent and incubation for 20 min at room temperature. Fast and high-throughput. Assays using 96-well plates and liquid handling system could allow simultaneous processing tens of thousands of samples per day. Storage conditions The kit is shipped on ice. Store all reagents at -20°C. Shelf life 6 months after receipt. 产品仅供科学研究禁止用于临床诊断、治疗 For Research Use Only. Not For Use In Diagnostic Procedures.

产品概述

Description

Xanthine is a purine base that can be found in most animal tissues and fluids. It is a product in the purine degradation pathway, produced by guanine deaminase from guanine, and by xanthine oxidoreductase from hypoxanthine. Xanthine is degraded to uric acid by xanthine oxidase. Clinically, xanthine and its derivatives act on sleep-inducing adenosine receptors as antagonists. Simple, direct and high-throughput assays for measuring xanthine find wide applications in research and drug discovery. MesGen Biotechnology xanthine assay kit uses a single Working Reagent that combines the xanthine oxidase reaction and color reaction in one step. The change in color intensity of the reaction product at 570 nm or fluorescence intensity at lex/em = 530/585 nm is directly proportional to xanthine concentration in the sample.

Application

Direct Assays: xanthine concentration in cell lysate, serum, and other biological samples.

Drug Discovery/Pharmacology: effects of drugs on xanthine (purine) metabolism.

Key features

Sensitive and accurate. Use as little as 10 μL samples. Linear detection range in 96-well plate for 10-15 minute incubation: 2 μM to 1 mM xanthine for colorimetric assays and 0.5 to 200 μM for fluorimetric assays.

Simple and convenient. The procedure involves addition of a single working reagent and incubation for 20 min at room temperature.

Fast and high-throughput. Assays using 96-well plates and liquid handling system could allow simultaneous processing tens of thousands of samples per day.

Storage conditions

The kit is shipped on ice. Store all reagents at -20°C.

Shelf life

6 months after receipt.

产品仅供科学研究禁止用于临床诊断、治疗

For Research Use Only. Not For Use In Diagnostic Procedures.

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