抗β-Tubulin鼠单克隆抗体,Anti β-Tubulin Mouse Monoclonal Antibody

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MAN1003

抗β-Tubulin鼠单克隆抗体,Anti β-Tubulin Mouse Monoclonal Antibody

-	100μl	1650.00	In stock
-	1ml	13800.00	In stock

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产品概述
Background This antibody detects a single clean band at 55kD representing beta Tubulin. This band is significantly reduced by using peptide blocking. The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins. Overview Description : Mouse monoclonal antibody to β-Tubulin [6C4] Reactivity : Mouse, Rat, Human Tested applications : WB, IHC, IF Formulation : Liquid Properties Immunogen : Recombinant full length protein, corresponding to amino acids 1-452 of Human Tubulin. Clonality : 6C4 Isotype : Mouse IgG1 Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB(1:1000-1:10000), IHC (1:50-1:200), IF (1:50-1:200) Storage instruction Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C For Research Use Only. Not For Use In Diagnostic Procedures.

产品概述

Background

This antibody detects a single clean band at 55kD representing beta Tubulin. This band is significantly reduced by using peptide blocking. The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. γ-tubulin is required to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competitive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins.

Overview

Description : Mouse monoclonal antibody to β-Tubulin [6C4]

Reactivity : Mouse, Rat, Human

Tested applications : WB, IHC, IF

Formulation : Liquid

Properties

Immunogen : Recombinant full length protein, corresponding to amino acids 1-452 of Human Tubulin.

Clonality : 6C4

Isotype : Mouse IgG1

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB(1:1000-1:10000), IHC (1:50-1:200), IF (1:50-1:200)

Storage instruction

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C

For Research Use Only. Not For Use In Diagnostic Procedures.

产品手册	MSDS	COA	参考
pdf word			1. Biomacromolecules.2016,17 (1) : 98–110 2. Cell Death Discovery. 2022, 8:142 ; https://doi.org/10.1038/s41420-022-00953-2

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