离子霉素 Ionomycin (free acid) | |||||||||
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产品货号 | 产品名称 | CAS号 | 包装 | 市场价(人民币) | 库存状态 | ||||
MG6613 | 离子霉素 Ionomycin (free acid) |
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产品概述 | |
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Size : 14.1 mM*100 μL in Ethanol
Molecular Weight : 709.01
Molecular Formula : C₄₁H₇₂O₉
Description
Ionomycin is more effective than A23187 as a Ca++ionophore. Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons.
Highly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+). More effective than antibiotic A23187 as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, causing significant absorption in the UV range; however, in contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines.
Highly specific for divalent cations and more effective than A23187 as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G1 phase in mature Burkitt lymphoma cell lines.
Storage condition
-20°C
For Research Use Only. Not For Use In Diagnostic Procedures.
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产品手册 | MSDS | COA | 参考 |
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